version 1.0.7

• Sensitive mode removed from TARDIS.
• --no-mei option added to skip MEI clustering. Helps faster runs if the user is not interested in mobile elements, but might increase false positive rate due to similar clustering rules to other types of SVs.

Download tardis-1.0.7.tar.gz, which includes the dependencies.

tardis-1.0.7_x86_64 is the precompiled binary. Dependencies are statically linked.

version 1.0.6

• VCF header fixes to define variables used in the INFO field.

Download tardis-1.0.6.tar.gz, which includes the dependencies.

tardis-1.0.6_x86_64 is the precompiled binary. Dependencies are statically linked.

version 1.0.5

• Various bug fixes
• SONIC version bump to 1.2

Download tardis-1.0.5.tar.gz, which includes the dependencies.

tardis-1.0.5_x86_64 is the precompiled binary. Dependencies are statically linked.

v1.0.4

• Minor bug fixes.

Download tardis-1.0.4.tar.gz, which includes the dependencies.

tardis-1.0.4_x86_64 is the precompiled binary. Dependencies are statically linked.

v1.0.3

• SONIC repo is updated.
• Initial implementation of breakpoint resolution.

Download tardis-1.0.3.tar.gz, which includes the dependencies.

tardis-1.0.3_x86_64 is the precompiled binary. Dependencies are statically linked.

v1.0.2

• Bug fix in heap resize
• Updated htslib to v1.9

Download tardis-1.0.2.tar.gz, which includes the dependencies.

tardis-1.0.2_x86_64 is the precompiled binary. Dependencies are statically linked.

v1.0.1

• Crash in some BAM files is fixed.

Download tardis-1.0.1.tar.gz, which includes the dependencies.

tardis-1.0.1_x86_64 is the precompiled binary. Dependencies are statically linked.

v1.0

• New probabilistic framework
• Genotyping
• Various bugfixes

v.0.7.5

• TARDIS now generates fragment size (i.e., insert size) histograms for each library if gnuplot is installed. Skips plot generation if gnuplot is not available.
• --hist-only parameter generates histograms only, then quits. Can be used for fragment size QC.

Download tardis-0.7.5.tar.gz, which includes the dependencies. tardis-0.7.5_x86_64 is the precompiled binary.

v0.7

• Improvements in multiple BAM/CRAM input. Tested up to 25 CRAM files at low coverage (1000 Genomes).
• Multiple BAM/CRAM files can now also be passed as comma separated list using the --input/-i parameter.
• More changes to memory management.
• Clean up deprecated code.
• Happy Republic Day, Turkey!

Download tardis-0.7.tar.gz, which includes the dependencies.