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ISMRM 2022 Abstract. A multi-task generative network for simultaneous post-contrast MR image synthesis and tumor segmentation: application to brainstem glioma

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yXiangXiong/MR-Brainstem-Glioma-Synthesis

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Pix2pixHD based Multi-task Generative Model

To reduce the exposure of Gadolinium-based Contrast Agents (GBCAs) in brainstem glioma detection and provide high-resolution contrast information, we propose a novel multi-task generative network for contrast-enhanced T1-weight MR synthesis on brainstem glioma images. The proposed network can simultaneously synthesize the high-resolution contrast-enhanced image and the segmentation mask of brainstem glioma lesions.

Image-to-image translation at 512x512 resolution

  • {T1, T2, ASL}-to-{T1ce, tumor mask}

Prerequisites

  • Linux or Windows
  • Python 3
  • NVIDIA GPU (11G memory or larger) + CUDA cuDNN

Getting Started

Installation

pip install dominate
  • Clone this repo:
git clone https://github.com/yXiangXiong/Multi-task_Generative_Synthesis_Network
cd pix2pixHD_Multi-task_Learning

Testing

  • Test the model (bash ./scripts/test_1024p.sh):
#!./scripts/test.sh
python test.py --dataroot F:\xiongxiangyu\pix2pixHD_Mask_Data --name NC2C --label_nc 0 --input_nc 9 --output_nc 6 --resize_or_crop none --gpu_ids 0 --which_epoch 200 --no_instance --how_many 144

The test results will be saved to a html file here: ./results/NC2C/test_latest/index.html.

More example scripts can be found in the scripts directory.

Training

  • Train a model at 512 x 512 resolution (bash ./scripts/train_512p.sh):
#!./scripts/train.sh
python train.py --dataroot F:\xiongxiangyu\pix2pixHD_Mask_Data --name NC2C --label_nc 0 --input_nc 9 --output_nc 6 --netG global --resize_or_crop none --gpu_ids 0 --batchSize 1 --no_instance
  • To view training results, please checkout intermediate results in ./checkpoints/NC2C/web/index.html. If you have tensorflow installed, you can see tensorboard logs in ./checkpoints/NC2C/logs by adding --tf_log to the training scripts.

Citation

If you find this useful for your research, please use the following.

Acknowledgments

This code borrows heavily from pix2pixHD.

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ISMRM 2022 Abstract. A multi-task generative network for simultaneous post-contrast MR image synthesis and tumor segmentation: application to brainstem glioma

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