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Shiny App providing functionalities to browse an query results of genome-wide CRISPR-Cas9 cancer cell line screens as well as cancer cell line transcriptomics data and predicted sgRNAs.

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CRISPRepo

Shiny app for CRISPR-Cas9 screen repository

global.R: establishes database connection and initialized global variables server.R: handles application logic upon user input ui.R: defines graphical user interface of the application

Neccessary files (indicated with relative path) to deploy the Shiny-app:

*) databases/screen.db (SQLite database file mounted with all dropout and drug-modifier screen data)

*) databases/screen_facs.db (SQLite database file mounted with all facs-based screen data)

*) databases/sgRNAs.db (SQLite database file mounted with all genome-wide sgRNA predictions for mouse and human, including prediction and validation analysis results)

*) dict/dict_joined.txt (Gene dictionary table for mouse/human homologs)

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Shiny App providing functionalities to browse an query results of genome-wide CRISPR-Cas9 cancer cell line screens as well as cancer cell line transcriptomics data and predicted sgRNAs.

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