TissueTMDD

TissueTMDD is a shiny that provide an interactive way to run simulations of drug-target binding in tissue interstitial space.

Using TissueTMDD, you can:

• Setup simulation parameters,
• Run simulations,
• Compare simulations,
• Export and import simulation settings

Installation

Prerequisites

• Git Installation and GitHub setup (instructions),
• R Installation (>= 4.3.0),
• RTools Installation (for Windows users, instructions).

Install {rClr}

rClr cannot be installed from github or from CRAN directly, use the following code to do so:

install.packages("https://github.com/Open-Systems-Pharmacology/rClr/releases/download/v0.9.2/rClr_0.9.2.zip", 
                 type = "binary")

Install TissueTMDD

# install.packages("remotes")
remotes::install_github("esqLABS/TissueTMDD@release")

To install the latest development version, use:

# install.packages("remotes")
remotes::install_github("esqLABS/TissueTMDD")

Installation (bis)

If the previous solution did not work, you can try the following

1. Download the source code here
2. Unzip it and open the .Rproj file with RStudio.
3. Run install.packages("renv") in the R console.
4. Run renv::restore() in the R console.
5. In the top menu bar, click on Build > Install Package

Run the App

library(TissueTMDD)
run_app()

Code of Conduct

Please note that the TissueTMDD project is released with a Contributor Code of Conduct. By contributing to this project, you agree to abide by its terms.