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hra-cell-embeddings

A repo to capture cell embedding visualizations

Handbook Explanation

In the handbook folder, a Visualization Handbook is used to justify our visualization settings and showcase how our design evolved.

Code Explanation

Visualization

  1. Basic Visualization - Mapping the cell type labels with the h5ad source file: here, we adopt two kinds of normalization strategies to normalize the matrix in h5ad source file to improve the readability of the visualization. As shown below: Example of the Visualization after normalization Example of the Visualization after normalization - Better view
  2. Visualization Tuning - PCA-200 + tSNE / Visualization Tuning - PCA-1000 + tSNE: we adopt the PCA algorithm for 200/1000 dimensions and then for t-SNE algorithm, with the same normalization settings in the Basic Visualization jupyter notebook. The visualization for the PCA setting of 1000 is shown below: PCA-1000 + tSNE
  3. Visualization Tuning the top 24 cell types - PCA-200 + tSNE: we visualize the top 24 cell types as shown below: Top 24, PCA-1000 + tSNE

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A repo to capture cell embedding visualizations

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