Skip to content

This project explores the PBRM1-PIAS1 interaction in epithelial differentiation through ChIP-seq analysis, highlighting EZH2's role and implications for cholesterol biosynthesis in cellular processes.

Notifications You must be signed in to change notification settings

OrangePomeranian/ChiP-seq

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

3 Commits
 
 
 
 

Repository files navigation

ChiP-seq

This GitHub project combines comprehensive ChIP-seq analysis to investigate PBRM1-PIAS1's role in epithelial tissue differentiation, using the GSE228221 dataset. It encompasses QC, mapping (bowtie2), peak calling (macs2), motif discovery, and target gene analysis, emphasizing EZH2's significance. By integrating bioinformatics techniques, the project enhances our understanding of epidermal differentiation and cholesterol biosynthesis. This study not only identifies potential PBRM1-PIAS1 targets but also explores the regulatory mechanisms and genetic regulation in epithelial tissues, highlighting the impact on cellular differentiation.

About

This project explores the PBRM1-PIAS1 interaction in epithelial differentiation through ChIP-seq analysis, highlighting EZH2's role and implications for cholesterol biosynthesis in cellular processes.

Topics

Resources

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published