How to set the parameters of cross-validation

[sunliangxing]

Dear Author:
I am new to machine learning.
When I am using crossvalidation I don't know how to set its parameters, I check the pdf in the article, crossval_o2m_adjR2(rna, metab, 1:3, c(0,1,5,10), c(0,1,5,10), nr_folds = 2, nr_cores = 4) I don't know which of these 1:3, c(0,1 ,5,10), c(0,1,5,10) how about determining. For example I have two matrices with 6 rows and 3000 columns. Should I take the columns randomly or is there any requirement?
Here's a partial screenshot of my data


Looking forward to your reply, thanks!